The infuriated Octavio stabs Jarocho in the stomach. Cofi is about to win, but Jarocho shoots him. Struggling financially, Octavio accepts a challenge by Jarocho to participate in a private dogfight, with no outside bets. Afraid, Ramiro steals the money and leaves with Susana. Octavio makes enough money to flee with Susana, and pays Mauricio, the owner of the dogfighting venue, to get Ramiro beaten up. Jarocho keeps entering new dogs into the fights, only for Cofi to kill them. Made aware of this by his friend Jorge and needing money to start his new life with Susana, Octavio decides to become involved in the dogfighting scene. Eventually, Jarocho sics his dog on Octavio's rottweiler, Cofi, but his own dog is killed instead. Local thug Jarocho, happy after winning in a dog fight, lets his dog loose on some strays and is threatened by a vagrant wielding a machete. Octavio tries to persuade her to run away with him. Octavio ( Gael García Bernal) is in love with his brother's wife Susana ( Vanessa Bauche) and dislikes the way she is abused by his brother Ramiro ( Marco Pérez). The film is constructed from three distinct stories linked by a car accident that brings the characters briefly together. 6 Film's role in Mexico's outlawing of dog fighting.Amores perros was nominated for the Academy Award for Best Foreign Language Film in 2000 and won the Ariel Award for Best Picture from the Mexican Academy of Film.

The soundtrack includes songs by Latin American rock bands including Café Tacuba, Control Machete, and Bersuit Vergarabat. The film was released under its Spanish title in the English-speaking world, although it was sometimes translated as Love's a Bitch in marketing.

The title is a pun in Spanish the word 'perros', which literally means 'dogs', can also be used to refer to misery, so that it roughly means 'bad loves' with canine connotations.

The stories are linked in various ways, including the presence of dogs in each of them. The stories centre on a teenager in the slums who gets involved in dogfighting a model who seriously injures her leg and a mysterious hitman. The film is constructed as a triptych: it contains three distinct stories connected by a car accident in Mexico City. It makes use of the multi-narrative hyperlink cinema style and features an ensemble cast. Amores perros is the first installment in González Iñárritu's 'Trilogy of Death', succeeded by 21 Grams and Babel. Amores perros is a 2000 Mexican psychological drama film directed by Alejandro González Iñárritu and written by Guillermo Arriaga.

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